ethyl 2-(4-chloro-3-cyanophenyl)-2,2-difluoroacetate - Names and Identifiers
ethyl 2-(4-chloro-3-cyanophenyl)-2,2-difluoroacetate - Introduction
ethyl 2-(4-chloroo-3-cyanophenyl)-2,2-difluoroacetate is an organic compound with the chemical formula C11H7ClF2NO2.
Nature:
-Appearance: colorless liquid
-Boiling point: About 230 degrees Celsius
-Density: about 1.36 g/mL
-Melting point: About -10 degrees Celsius
-Solubility: Soluble in organic solvents such as chloroform, ether and benzene
Use:
- ethyl 2-(4-choro-3-cyanophenyl)-2,2-difluoroacetate is widely used as pesticide intermediates and pharmaceutical intermediates.
-It can be used to synthesize various pesticides, insecticides, herbicides and glyphosate.
Method:
ethyl 2-(4-choro-3-cyanophenyl)-2,2-difluoroacetate can be synthesized by the following steps:
1. In the presence of sodium cyanide, P-chlorobenzoic acid and hydrofluoric acid Ketal are 2-chlorophenylbenzoic acid.
2. Esterification of 2-chlorophenyl benzoic acid and hypochloro-aminoalanine.
3. Cyanation reaction was carried out under acidic conditions to obtain ethyl 2-(4-chroo-3-cyanophenyl)-2,2-difluoroacetate.
Safety Information:
ethyl 2-(4-choro-3-cyanophenyl)-2,2-difluoroacetate is a chemical and should be handled and stored in accordance with correct safe operating procedures.
-This compound may be irritating to the eyes and skin. Rinse with plenty of water immediately after contact.
-During operation and storage, avoid inhaling its vapor and dust, because it may be harmful to the respiratory system.
-It should be kept away from fire and high temperature, stored in a dry, well-ventilated place.
-When using or disposing of this compound, follow local regulations and safe operating procedures.
Last Update：2024-04-09 02:00:51